Assess Liver Health In Vivo

The liver is the single most important regulator of metabolic homeostasis at the organismal level in vertebrates and performs multiple crucial biological functions including detoxification of xenobiotics, protein metabolism, degradation of waste products, vitamin storage, and bile acid production. Metabolomics is an indispensable tool for capturing an integrative profile of an individual’s liver function. As the incidence of certain liver diseases, such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) continue to rise, researchers and healthcare providers can look to Metabolon to provide much-needed diagnostic and prognostic indicators to better understand the molecular mechanisms underpinning pathological processes. As the world leader in both metabolomics and lipidomics services, Metabolon is uniquely positioned to capture liver disease phenotypes through the broadest possible lens.

Once you see the full value of metabolomics, the only remaining question is who does it best? While many laboratories have metabolite profiling or analytical chemistry capabilities, comprehensive metabolomics technologies are extremely rare. Accurate, unbiased metabolite identification across the entire metabolome introduces signal-to-noise challenges that very few labs are equipped to handle. Also, translating massive quantities of data into actionable information is slow, if not impossible, for most because proper interpretation takes two things that are in short supply: experience and a comprehensive database.