Vancomycin Single Analyte Assay

Metabolon Target

Vancomycin Single Analyte Assay

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About Vancomycin

Vancomycin is an antibiotic medication that is used to treat infections in many different parts of the body. Intravenous treatment with vancomycin is used to treat infections caused by susceptible microorganisms resistant to penicillin or for anti-bacterial prophylaxis in penicillin-hypersensitive individuals. When taken orally, vancomycin is used to treat an infection of the intestines caused by Clostridium difficile that causes severe diarrhea. Oral vancomycin is also used to treat staph infections that can cause enterocolitis, an inflammation of the small intestine and colon.

Metabolomics reveals biological insights otherwise unseen. For a successful metabolomics study, both small molecule discovery and the ability to dig deeper into specific biomarkers of interest are needed to uncover actionable insights that propel new therapeutic developments. A specific combination of liquid chromatography-mass spectrometry (LC-MS) technology and expertise is required to identify these biomarkers of interest and develop assays that are sensitive enough to explore them fully.

At Metabolon, we understand the crucial role vancomycin plays in infection and inflammation, and we’ve established best-in-class expertise for its detection. This assay can be used to track vancomycin and enhance biological understanding across preclinical and clinical research.

Vancomycin Single Analyte Assay Details

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LLOQ
Feces
2.00 µg/g
Analysis Method and Instrumentation:
LC-MS/MS (Agilent 1290 UHPLC/Sciex QTrap 5500)
Sample Type and Required Amounts
Sample Type Sample Requirements
Feces 200 to 500 mg (wet weight)
Others on request

Disclaimer: This method is for Research Use Only and is not to be used for diagnostic purposes.

Delivering Absolute Quantification for Research and Biomarker Analysis

Our readily available or custom developed quantitative assays help you achieve your research and biomarker validation objectives with precise and fully validated methods. Our targeted assays and panels cover >1,000 metabolites and lipids across a wide range of biochemical classes, metabolic pathways, and physiological processes, and they can be customized to best fit any application.

Vancomycin Single Analyte Assay Applications

Gut Health

Gut health is important for overall health. Alterations of the gut microflora can cause several types of gastrointestinal disorders (including irritable bowel syndrome and viral hepatitis. In addition, gut microflora has also been implicated to play a role in autoimmune disease, skin disorders, as well as in diabetes and obesity. The unique ability for metabolomics to identify microbial metabolites and how they regulate pathways in the host makes the technology a valuable tool for understanding gastrointestinal and other metabolic disorders.
gut health

Big Insights with Metabolon

Cited in over 3,000 publications, we help scientists and manufacturers gain greater insight into their studies through metabolomics. See how our approach can become a successful part of your workflow.

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