Working With Us

Deliverables

Metabolon’s solution ensures the maximum value, utility, and applicability of your data to advance your research objectives. We offer end-to-end service for all our products, from study design to data reporting.

Client Data Table

Data interpretation is tiered depending on client needs. Every tier includes the Client Data Table (CDT). The CDT is a collection of data deliverables to help clients review, analyze, and understand their project data. The format makes it easy to import study data into popular analysis and statistical tools, such as R or Python, with a consistent format. Every project includes full metabolite data in Excel format.

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Targeted Panels and Single Analyte Assays

In addition to the Client Data Table, absolute quantitative measurements are provided as part of a sample analysis report with a description of reference chemicals and matrices used during sample analysis. If the Targeted Panel is part of a Discovery study, statistics and interpretation may be provided. Custom panels and assays include a final assay protocol and method validation report.

Complex Lipids Targeted Panel

In addition to the CDT, the Complex Lipids Targeted Panel also comes with access to Surveyor, a suite of custom-designed data visualization and analysis software tools. Two primary tools exist within Surveyor for interpreting the data—Pathway Mapping Tools and Discovery Tools.
Complex Lipids Targeted Panel
Pathway Enrichment

Pathway Mapping Tools

The Surveyor pathway maps allow clients to understand their lipidomic data in the context of lipid metabolic pathways. Each pathway has been curated and annotated by Metabolon experts, and each element of the map is interactive, providing both data analysis (boxplots and difference testing) and additional information on each metabolite or activity. Using Pathway Mapping tools, researchers can investigate the effect of their comparisons on the concentration and fatty acid composition of different pathways, including:

  • Complex Lipid Metabolism (phospholipids and neutral lipids)
  • Sphingolipid Metabolism (ceramides and sphingomyelin)
  • Fatty Acid Metabolism

Discovery Tools

Discovery tools allow clients to perform an unbiased evaluation of the performance of each lipid and layer in biological information and structure when desired. The tools plot all of the measured lipids and allow clients to filter and sort results to aid in the identification of biomarkers. The Biomarker Performance page provides a comprehensive view of the performance of each lipid marker in separating the treatment groups. The Time Course/Multiple Comparisons page improves the analysis of time-course and multiple-treatment comparisons by allowing clients to simultaneously plot multiple comparisons between groups. In both tools, each plot point is interactive, linking a selected lipid marker to additional information about their structure and biology, including related box plots.

Global Discovery Panel: Full Interpretation & Consultative Support

For projects that include a Discovery Panel, the CDT comprises three individual files with heat maps and box plots in separate Excel and pdf files. This video walks through examples of each of these files with attention focused on the features, layout, information, and the user benefits of each. In addition to the CDT, you may also add on a statistical analysis of your data with univariate significance tests (t-tests, ANOVA, repeated measures analysis, etc.) performed by our experienced informatics team. Statistics, along with heat maps and box plots, are viewable in the MyMetabolon client portal for visualizing and analyzing your study data.

Full custom interpretation by our experienced team of more than 20 PhD study directors is available for Discovery Panels, leveraging our proprietary biochemical pathway knowledgebase and powerful bioinformatics. Interpretation may include a comprehensive summary of actionable biological insights and recommended next steps. Your study may benefit from additional post-project support and a live consultation with your study director to help answer any questions and move forward with your research.

See how Metabolon can advance your path to preclinical and clinical insights

Why Metabolon?

Once you see the full value of metabolomics, the only remaining question is who does it best? While many laboratories have metabolite profiling or analytical chemistry capabilities, comprehensive metabolomics technologies are extremely rare. Accurate, unbiased metabolite identification across the entire metabolome introduces signal-to-noise challenges that very few labs are equipped to handle. Also, translating massive quantities of data into actionable information is slow, if not impossible, for most because proper interpretation takes two things that are in short supply: experience and a comprehensive database.

Only Metabolon has all four core metabolomics capabilities

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Coverage

Ability to interrogate thousands of metabolites across diverse biochemical space, revealing new insights and opportunities

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Comparability

Ability to integrate the data from different studies into the same dataset, in different geographies, among different patients over time

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Competency

Ability to inform on proper study design, generate high‐quality data, derive biological insights, and make actionable recommendations

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Capacity

Ability to process hundreds of thousands of samples quickly and cost‐efficiently to service rapidly growing demand

Partner with Metabolon to access:

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A library of 5,400+ known metabolites, 2,000 in human plasma, all referenced in the context of biochemical pathways

  • That’s 5x the metabolites of the closest competitor
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Unparalleled depth and breadth of experience analyzing and interpreting metabolomic data to find meaningful results

  • 10,000+ projects with hundreds of clients
  • 2,000+ publications covering 500 diseases, including numerous peer-reviewed journals such as Cell, Nature and Science
  • Nearly 40 PhDs in data science, molecular biology, and biochemistry

Using our robust platform and visualization tools, our experts are uniquely able to tell you more about your molecule and develop assay panels to help you zero in on the results you need.

Contact Us

Talk with an expert

Request a quote for our services, get more information on sample types and handling procedures, request a letter of support, or submit a question about how metabolomics can advance your research.

Corporate Headquarters

617 Davis Drive, Suite 100
Morrisville, NC 27560

Mailing Address:
P.O. Box 110407
Research Triangle Park, NC 27709

+1 (919) 572-1711

+1 (919) 572-1721